An expansive genomic resource.
Mitch Weiss, Ph.D.
Mitch Weiss, Ph.D.

Non-Cancerous Diseases

Welcome to the Non-Cancerous Diseases Research Domain

On this page, we have gathered all you need to know about the data and analysis tools we offer for non-cancerous diseases on St. Jude Cloud. We currently feature one study, the Sickle Cell Genome Project, but we are working to expand our repository to include more. Use this page for direct access to all current and future non-cancerous diseases, or discover the possibilities of data curation with our list of recommended apps for working with non-cancerous disease data. Get updates and important links on this page to know what St. Jude Cloud is up to next!


Vaso-occlusive pain crisis (VOC) is the most common complication of sickle cell disease and correlates strongly with higher hospital visits and increased mortality. The genetics of VOC in sickle cell patients is poorly understood. We identified risk variants associated with shorter time to first pain event.

View Pain Study

Kidney damage in individuals with sickle cell disease begins in infancy and can progress to kidney failure, which has a high mortality rate. Urinary albumin excretion (albuminuria) is a sensitive marker of early kidney damage in individuals with sickle cell disease. We identified combinations of variants in the APOL1 gene that are correlated with developing albuminuria earlier in childhood.

View Renal Study


We offer data from several studies, include the Sickle Cell Genome Project. Learn about the whole-genome sequencing data provided to academic researchers through St. Jude Cloud.

Sickle Cell Genome Project
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